The State AIDS Project Cell was formed in January 1993 in Tamil Nadu. TAMIL NADU STATE AIDS CONTROL SOCIETY (TANSACS) was the first registered Society in India for HIV/AIDS control and prevention registered in 1994 as a mandate of National AIDS Control Organisation (NACO), New Delhi. The Principal Secretary to Government, Health and Family Welfare Department, is the President of the Society and a Senior I.A.S. Officer is the Member Secretary & Project Director.

The sentinel surveillance data has been showing a steady decline among antenatal clinic attendees since 2001. A total of 2.13 lakh persons have tested positive for HIV in the state. In 1986 the first HIV case in India was detected in Madras Medical College, Chennai.

TANSACS' foundation is built on quality care-and-support system for persons living with HIV/AIDS. By fostering close collaboration with Non Governmental Organisations, women's self-help groups, Community Based Organisations, positive people's networks and various National and International Donor Agencies.

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